The behavior of the nonlinear hinges was defined by using backbone curves based on current design codes of KCI 2012 and ACI 318-11.
Six kinds of intron patterns (a– f) within the basic and hinge regions are defined.
O3 and O4 are defined as center of the two U hinges, respectively.
Hinge regions that allow for substantial flexibility of the subdomains are defined.
The assigned plastic hinges at capable plastic points and also the acceptance criteria for rotational and translational displacements are defined to models as Tables 3, 4 and 5.
The hinge motion in hDHFR is likely mediated by hinge loops longer than those present in ecDHFR: in hDHFR, hinge 1 is defined as residues Thr39 Leu49 and hinge 2 as His127 Leu131, compared to Thr36 Pro39 and Pro105 Gln108 in ecDHFR, respectively.
Closed-form compliance equations are derived for a two-axis flexure hinge that is defined by two non-identical parabolic profiles.
Open image in new window Note: The core hinge region is defined by the N-terminal and C-terminal cysteines that link the two heavy chains together (Liu and May , 2012.
The "opening point" of hinge loops is defined here as the boundary between two well-superimposable main domains and the non-superimposable regions that cover the swapped domains.
Four kinds of intron patterns (a d) within the basic and hinge regions were defined and additional conserved motifs were identified, both presenting high group specificity and supporting the group classification.
