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We propose that these uAUGs represent a subset of miRNA interaction sites on 5'-UTRs in miBridge, whereby a miRNA binding a uAUG hinders the progression of ribosome scanning the mRNA before it reaches the open reading frame (ORF).
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However, the stage of disease progression at which surgery is necessary remains undefined, and limited scientific evidence is available regarding surgical methods that hinder the progression of the disease over time.
In one scenario, the domain might interact with elements of the nuclear envelope that hinder the progression of the protein in the nuclear pore.
Conversely, the suppression of Rac1 hindered the progression of EMT by TAK1-deficient cancer cells.
The need for new, cost-effective treatments to prevent or hinder the progression of adult caries is considerable.
Therefore, a short-term treatment with C188-9 hindered the progression of preexisting early lesions and removed the stimulatory effect of pregnancy on breast cancer risk.
Antiangiogenic drugs function by inhibiting formation, maintenance, and development of blood vessels and therefore act in hindering the progression of endometriosis [ 77].
The remaining three gaps (HoxB2- HoxB1, HoxC12- HoxC11 and HoxC8- HoxC6) may have been due to either enlarged gene distances or complex structures that hindered the progression of the Taq DNA polymerase.
Alterations in the DNA structure that hinder the progression of RNA polymerases during transcription are highly toxic for the cell and, if not properly resolved, can lead to cellular apoptosis or senescence (Ljungman and Zhang 1996; Ljungman and Lane 2004).
We found a slightly lower risk for aggressive compared with non-aggressive tumours, indicating that aspirin might be more influential in hindering the progression than development of prostatic tumours.
To explore the possible mechanisms through which cyproheptadine elicits its growth inhibitory effect, we determined if treatment with cyproheptadine hinders the cell cycle progression of HCC cells in concentration ranges close to the IC50 values.
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CEO of Professional Science Editing for Scientists @ prosciediting.com