Sentence examples for hinders the efficacy from inspiring English sources

Multidrug resistance (MDR) is a major obstacle that hinders the efficacy of chemotherapy in many human malignancies.

Head and neck tumors are highly hypoxic in nature and also show accelerated proliferation of clonogenic tumor cells during the course of treatment, which hinders the efficacy of radiotherapy and leads to locoregional treatment failure [ 4, 5].

Organo-mineral complexes may hinder the efficacy of microbial enzymes to degrade organic C [6, 10, 11].

These and the other researchers have emphasized the need to quantify and effectively remove the poorly understood biases that are hindering the efficacy of MI as a measure of coevolution [4] [9].

As human infection with H1N1 viruses continue to increase, so too does the likelihood of antigenic drift and shift leading to generation of novel viruses with potential for higher morbidity and mortality rates and hindering the efficacy of current vaccines.

In a recent publication, buyers were admonished to beware of the potential for ingested CAM to cause side effects or hinder the efficacy of conventional therapies [ 33].

In our study, we demonstrated that Sorafenib induced cell cycle arrest by decreasing the proportion of cells in the S and M phase hindering the efficacy of cytarabine.

However, Escobar-Páramo et al. (2012) showed that application of antibiotic rifampicin against the host bacteria of a phage decreased the survival of phages in the system and would therefore potentially hinder the efficacy of combined phage and antibiotic treatments.

As such, the majority of pharmacological interventions are targeted at alleviating depressive symptoms primarily to improve quality of life and improve functioning in AD and secondarily to mitigate factors exacerbating cognitive impairment and hindering the efficacy of pro-cognitive drugs and other non-pharmacological interventions.

For instance, in selecting between two opioid analgesics for palliative care, perhaps the ADR that physicians most like to avoid is vomiting, which, although not a severe ADR, may hinder the therapeutic efficacy and decrease patient quality of life.

Otherwise, sonication turned the homogenate unclear and hindered the TPP efficacy on fractioning proteins.