Sentence examples for hinders sequence from inspiring English sources

Apparently, the presence of an inserted domain within the AvrB β-hairpin, combined with an alteration of several active site motif residues hinders sequence recognition.

The highly diversified and duplicated genome hindered sequence assembly and complicated the genome annotation as well as SNP identification.

Moreover, it should be noted that prophages often contain homologous sequences inserted at different loci around the genome, hindering sequence assembly efforts.

Furthermore, the nature of highly diversified and duplicated genome of fish species hindered sequence assembly and complicated the genome annotation as well as SNP identification.

However, Wang et al. [ 19] used a combination of de novo and alignment methods as the large divergence time between black grouse and domestic chicken (Gallus gallus) used as a reference (~30-40 ~30-40ay hinder sequences fromyaligning properly.

These differences may result from copy number variants and chromosomal rearrangements hindering automated sequence assembly of the equine genome [ 21].

Furthermore, very long DNA molecules span complex genomic regions that are rife with repeats that generally hinder accurate sequence assembly without Optical Mapping analysis.

The large genomes of conifers have greatly hindered their sequencing (but see [ 5]), but they have also prompted large-scale investigations of expressed gene sequences for the inference of putative unigene sets (reviewed by McKay and Dean [ 6]) and initiatives to map these genes (reviewed by Ritland et al. [ 7]).

Repetitive stretches of DNA are abundant and are one of the main technical challenges that hinder accurate sequencing and genome assembly efforts [ 1].

In particular, repetitive TEs create ambiguities in alignments and assemblies of short sequences (e.g., data typically produced from so called next-generation sequencing), which prejudice meaningful interpretations and hinders large-scale sequencing of complex genomes (Berkman et al. 2012).

However, the inability to BLAST any DNA or amino acid sequence hindered us from finding the tRNA-trp in the genome.