Sentence examples for hinders approach from inspiring English sources

The 6β-hydroxymethyl group sterically hinders approach of the water molecule as well as restraining the side chain of E166 that facilitates hydrolysis.

Somewhat diminished activity for H6 (compared to H5), when the alkyl group is moved from sulfenyl sulfur to ester oxygen, hinders approach to the carbonyl carbon, suggesting that it may be serving as an electrophile.

Using the crystal coordinates of taurolidine the first hydrolysis (Figure 1) showed limited space for a non hindered approach of water to cleave the exocyclic C-N bond and, even after modifying rotational bond angles of taurolidine to achieve more clearance, we could not find a reaction path.

In the absence of the analyte cation, electrostatic repulsion between the marker anions and the carboxylate groups of the receptor monolayer hindered the approach of the marker anion to the electrode surface and hence hindered its reduction.

Buck reiterated that point: Davis cannot become so consumed by his statistics that he lets it hinder his approach.

For fellow New Zealand-born director Regan Hall his own gender has not hindered his approach to his first feature, Fast Girls, a female-centred story about British relay athletes to be released next month before the London olympics.

However, the complexity associated with the large combinatorial retrosynthesis design space has often been recognized as the main challenge hindering the approach.

Three major obstacles were hindering this approach: A number of databases did not allow or did not enable batch downloads and storage of compound lists and structures.

The high frequency of null alleles at the 2L marker precluded the scoring of markers on all three chromosomes in the full sample set, thus hindering one approach to addressing the above question, as F1 and backcross progeny could not be reliably distinguished.

Conversely, the negative electrostatic potential of the cavity would be expected to hinder the approach and binding of negatively charged peptides (especially with charges in the C-terminal moiety) an observation that could explain the negative effect of glutamate residues in peptide degradation.

ventralis, J. ornatus, and E. cyanostictus hindering this approach for now.