The substantial accumulations of pyruvate and TCA cycle C6 intermediates were observed during aerobic fermentation which hindered achieving the maximum succinate theoretical yield.
This fundamental limit has hindered achieving the second requirement (ie the evaluation of tissue-specific or tumor-specific promoters for transcriptional targeting of therapeutic genes in the context of in vivo models of breast cancer) [ 105].
These almost null findings may be related to a pre-existing high standard of shared decision making realisation in the physicians' guidance of patients or circumstances in the inpatient treatment setting that hinder achieving further improvements through the introduction of decision aids.
However, neurosurgeons are currently hindered in achieving complete resections because of indistinct tumor margins and microscopic tumor infiltrating several centimeters into the surrounding brain, which is impossible to detect with currently available methods.
Despite economic growth of 5%to6%6% a year since the early 1990s, the poor nutritional status of Bangladeshi women and children undermines the health and wellbeing of all Bangladeshis, and hinders progress towards achieving the millennium development targets on maternal and child mortality and poverty.
The underlying litigation is about whether the state should end or limit non-academic course work that hinders students from achieving their academic goals.
Goal 3, "promote gender equality and empower women" needs to be expanded with a clear target of reducing lifetime IPV prevalence since violence against women hinders progress in achieving goal 3 and all other Millennium goals.
The tension and fun in a story comes when a problem is introduced, one that will hinder the characters achieving their goal.
Malevolent beings demons, fallen angels, ghosts, goblins, evil spirits in nature, hybrid creatures, the daevas of Zoroastrianism, the nārakas (creatures of hell) of Jainism, the oni (attendants of the gods of the underworld) in Japanese religions, and other such beings—hinder man in achieving a proper relation with God, the spiritual realm, or man's life situations.
We are comfortable with the organization of our culture as long as it does not hinder us from achieving our potentials.
