Sentence examples for hindering the binding from inspiring English sources
The phrase 'hindering the binding' is a correct and usable phrase in written English
You can use it to describe something that is preventing, interfering or obstructing the process of bringing two or more things together to form a single unit. For example, "The harsh sunlight was hindering the binding of the adhesive to the surface."
Treatment of lung cancer cells with histone deacetylase inhibitor will inhibit the suppressing function by hindering the binding to the target sequence [ 128, 129].
These binding sites can be inactive due to the occupancy of nucleosomes hindering the binding of the TF to the binding site in any genome.
Additionally, these proteins have relatively large flat surfaces, thereby hindering the binding of small chemical inhibitors, or even if binding occurs it is difficult to restrict interactions or functionalities on the large complex as a whole.
This is likely due to the low concentration of IgA in the serum [ 26] and possibly through the binding of the more abundant IgG to antigen, sterically hindering the binding of IgA in the assay.
When injected systemically or locally, antagomirs interact with miRNAs in the cytoplasm and hybridize specifically with the mature miRNA target hindering the binding of miRNA with their corresponding mRNA.
If this residue is an Ile it pushes the Trp against the Tyr, thus hindering the binding of BAL, whereas if it is an Ala or a Cys the Trp adopts a conformation that leaves enough room for productive BAL binding [ 19].
We observed an unexpected effect of a conserved mouse human framework position (L37) that hinders the binding of the humanized scFv to antigen.
On the other hand, a rigid binding site may also hinder the binding process as the ion has to perfectly align itself.
The combined four mutations F151S, A152S, F714S, F717S are therefore sufficient to hinder the binding of CaM to hEAG1 (p>0.05) BD-C1 and other auxiliary sites can still be involved in the binding mechanism in a cooperative manner.
One possible explanation is that full-length MUC1 contains a self-aggregation domain that likely contributes to the protein's characteristic clustering and could sterically hinder the binding of ligands to the adjacent region which is the Anti-MUC1* epitope.
With this methodology it is possible to identify fully complementary mAb pairs that would not sterically hinder the binding of each other to the same protein, e.g. for establishing a highly sensitive sandwich ELISA for PrPC and/or PrPSc.
