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More specifically, VEGF has been demonstrated in vitro to hinder the functional maturation of dendritic cells from their hematopoietic progenitors (Gabrilovich et al, 1996).
43 44 However, the lack of enteral feeds may hinder the functional maturation of the gastrointestinal tract, and the prolonged use of parenteral nutrition is associated with an increased risk of systemic infection due to the impairment of immune cell functions.
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Consequently, the functional assignments of many genes related to fat storage based on a single method may not be accurate and potentially hinders the functional studies of genes that control fat accumulation in C. elegans.
This prevents the analysis of homozygous mutations and hinders the functional analysis of their role(s) in specific cell types such as microspores.
First, certain co-factors might be required for Btd to efficiently activate its target gene transcription, and a lower abundance of these co-factors in type I neuroblasts hinders the functional output of mis-expressed Btd.
We excluded elderly individuals who had severe cognitive impairment that would hinder the examinations, patients with functional limitations that prevented ambulation and patients with inflammatory rheumatic diseases.
This approach was able to address and resolve complications that arise from alternative splicing, differential processing of the prohormone, and non-neuropeptide genes that hinder the experimental confirmation and functional characterization of neuropeptides.
Functional silos hinder the coordination necessary for companies to seize new business opportunities.
These functional groups hinder the charge transformation from BaCrO4 to GO layer.
However, LD between neighbouring SNPs, insufficient coverage of the locus and the use of univariate statistical methods hinder the identification of the true functional change.
Genetic and chemical approaches to identify key molecules in the vesicular mechanism seem to be hindered by the functional redundancy of the vesicle tethering and release complexes [ 6].
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