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Epigenetic markers may likewise hinder normal development: the offspring of parents who experience famine are at heightened risk for developing schizophrenia, some research suggests — perhaps because of the chemical signatures on the genes that parents pass on.
To minimize patronage, nepotism, and other forms of favoritism, government work is subject to myriads of regulations from hiring to contracting to public access that don't hinder normal business operations.
Possibly through this switch, the ischemic state could hinder normal fatty acid oxidation, which has been shown to result in left ventricular hypertrophy in humans and model organisms [16] [19].
Mutations may permanently hinder normal folding and in this case the risk of pathology increases as the unfolded proteins accumulate in the tissues causing aggregation and formation of insoluble fibrils and plaques [27].
Thus, a decrease in extracellular PPi may hinder normal bone remodeling, for instance, by inhibiting osteoclast differentiation or activity.
Further, excess delivery of therapeutic agents may create a competitive problem to some other biomolecules that may hinder normal functions of cells, cellular organelles, enzymes, and signaling molecules.
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Freestalls with a construction hindering normal lying, rising, and standing movements should be avoided.
The researchers suspect that painkillers upset the natural balance of male hormones at work in unborn baby boys and this hinders normal development.
This can be a considerable advantage, because adding a minimal extra sequence minimizes the risk of hindering normal functions of the labeled protein.
4. The child had a motor-control handicap which hindered normal participation in physical activity.
These factors cause a rise in skin surface pH, increasing the activity of proteases and lipases, thus hindering normal skin microflora and disrupting normal skin barrier integrity [ 6- 9].
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