However, consistent expression of the protein as insoluble inclusion bodies in bacteria host systems has largely hindered HBx manufacturing via economical biosynthesis routes, thereby impeding the development of anti-HBx therapeutic strategies.
But manufacturing challenges have hindered attempts at mass production.
Components are limited by manufacturing realities which can hinder designs concepts tremendously.
Lobbyists, including many hired by banks, have argued that the new rules are too broad and would hinder use of derivatives by manufacturing and transportation companies, for example, which use the products to manage fluctuations in energy prices.
For example, although a new car model configuration with component commonality may lower manufacturing cost, it also hinders increased revenues that could have been achieved through product differentiation.
The program underlines a growing concern that gaps in workers' skills will hinder the current renaissance of American manufacturing.
Nevertheless, these methods require complex processing steps that hinder the potential for integration into large-scale manufacturing processes.
If China continues to pursue huge trade and investment surpluses and to accumulate vast financial claims, it will hinder the necessary global economic adjustment, create excess manufacturing capacity, and lay the groundwork for the next crisis".
WHO guidelines shape demand, and their complexity may help or hinder achievement of economies of scale in pharmaceutical manufacturing.
When developing Prognostic and Health Management (PHM) applications for manufacturing systems, data acquired frequently comes with issues which hinder further data analysis.
WHO Guidelines heavily shape demand, and their relative complexity may help or hinder the achievement of economies of scale in pharmaceutical manufacturing.
