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There is a lack of consensus on which factors most influence adherence behaviour and methodological issues hinder interpretation of existing evidence.
However, difficulties in acquiring data from peripheral (e.g. information from muscle) during fMRI studies of motor function hinder interpretation of fMRI data and designing more sophisticated investigations.
Whilst the weight of the evidence suggests that there may be an association between vitamin D deficiency and AF, incomparable study designs and methodological limitations hinder interpretation of the current body of evidence.
However, most patient preference studies of these drugs conducted to date have serious design flaws that hinder interpretation of the data, and thus limit the utility of the results.
Since the assay on demand primer and probe available from ABI for Smn exon 7 are too close or overlap the C-T and 2B mutations and could hinder interpretation of results, we designed and validated FL-Smn and Δ7Smn assays to specifically amplify Smn transcripts with similar efficiencies between the WT, C-T and 2B mutations and not cross react with human SMN.
This does, however, hinder interpretation of whether anti-inflammatory effects are directed at OA itself or post-surgical inflammation.
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Indeed, genes linked to RTK signalling display pleiotropic functions during embryogenesis; the observed phenotypes, which affect several tissues as well as developmental processes, often hinder interpretations with regards to their role in trachea.
Our multicenter study was conducted in only three ICUs in the north of France and included a limited number of cases thus hindering interpretation of data.
On the other hand, setting L r too high has similar effects as the BTD model of a sinusoid source: artefacts are superimposed on the ictal signal even for high SNR values, hindering interpretation.
However, uncertainty as to the identity of the organisms that biosynthesize brGDGTs, the variation in the extent to which GDGTs represent end member carbon pools and the suspected production of brGDGTs and isoGDGTs in both marine and terrigenous environments hinders interpretation of the BIT index.
Due to a low count of suicides in some occupational groups, a number of estimates were unstable which hinders interpretation of results.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com