As expected, mutations within BRC repeats 1 4 led to a substantial reduction of Rad51 binding, whereas the S3291E substitution, which hinders interaction between TR2 and Rad51, largely retained Rad51 binding, likely mediated through the BRC motifs under this condition.
The contorted polymer chain forms a very stable morphology and substantially hinders interactions between chromophores, thus diminishing the formation of aggregated species that are commonly observed in other electrooptically active polymers.
Sibling molecules are the products of one replication event and are necessarily, at least transiently, co-localized, and hence not subject to all of the other barriers that might hinder interaction and recombination between two independent genomes.
The improvement could be attributed to the LaF3 coating layer that hinders interaction between LiCoO2 and electrolyte and stabilizes the structure of LiCoO2.
This process may hinder the interaction between peptide and carbon nanotubes/methylene blue and results in great decline of electrochemical signals.
Since all the developers do not have same background and understanding over the special areas, the knowledge difference between the developers, i.e., the specialization, can hinder the interaction between the team members.
Despite the wide utilization of these stealth agents, such hydrophilic coatings can sterically hinder the interaction between polyplexes and cellular membranes, resulting in lower transfection efficiency.
Secondly, the arrangement of the BiFC fusion proteins within a protein complex may sterically hinder an interaction between the complementary EYFP fragments and prevent the formation of functional EYFP [ 39].
Our data suggest that the recessive familial mutations that impair dimerization and protein stability of DJ-1 also hinder the interaction between DJ-1 and aSyn, which is in agreement with several familial PD mutations affecting normal DJ-1 function.
In view of the fact that sCD14 may hinder the interaction between LPS and the phagocyte membrane CD14, we herewith propose a model which aims to demonstrate that high sCD14 levels might contribute to shelter liver function through the down-regulation of the inflammatory cascade.
Once localized in the nucleus, reduced Trx1 hindered the interaction between AIF and DNA, thereby bringing about an attenuation of AIF-mediated DNA damage.
