Sentence examples for highly transforming from inspiring English sources

The latter response is intriguing in the light of the previous observation that Wnt-5A failed to induce transformation under conditions where Wnt-1 was highly transforming [ 8].

Moreover, only a few GEFs have been found mutated in human cancer despite the fact that many of them have been originally isolated as activated, highly transforming oncogenes.

Akt, also called protein kinase B (PKB), is the cellular homologue of the vAkt oncogene found in the highly transforming retrovirus AKT8 (Ahmed et al, 1993).

Certain serotypes of adenoviruses are also highly transforming in cell culture and in animal models but adenovirus DNA was generally not detected in human tumor cells.

EGFRvIII is characterised by deletion of 267 amino acids in the external domain of the receptor, which consequently is ligand-independent, constitutively active and highly transforming (Sugawa et al, 1990; Wong et al, 1992).

Subsequent experiments showed that Wnt-1 and Wnt-3A, but not all Wnt proteins, were highly transforming for mammary epithelial cells in vitro [ 8], and that Wnt-1 is overexpressed in breast cancer [ 9].

Orchards are parts of agriculture and apart from their economic role they may preserve biodiversity in highly transformed farmlands.

The apparent increase in richness may be due to maintenance of original vegetation-specific species in untransformed fragments in highly transformed areas combined with species that exploit transformed habitats well in the transformed areas.

The Tropical Dry Forest (TDF) is one of the most highly transformed and threatened neotropical systems in the world and much of its original area has been replaced by secondary forests.

We used direct gradient analysis to assess correlations between land-use and the composition of vegetation along a riparian river corridor in the highly transformed landscape surrounding Stellenbosch in South Africa's Western Cape Province.

Only trees at warmer sites showed symptoms of growth decline, most likely explained by water stress increase in the last decades affecting the highly transformed open (i.e. low competition) tree structure.