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VSSP, used as monotherapy, demonstrated a unique ability to render immunogenic highly tolerated gangliosides.
VSSP demonstrated a unique ability to render highly tolerated gangliosides immunogenic.
The treatment regimen was highly tolerated; we observed no significant weight loss.
Together, these experiments imply that the titanium salan complex 2 combines strong antitumor effects in vitro and in vivo and is highly tolerated when given at low doses distributed over multiple injections.
These results are consistent with the model in that highly tolerated substitutions were uncharged, similar to serine in size, while resistant residues could be either large or small, which repositioned the YMDD loop closer or further from the stabilizing alpha-helix containing L180M, and could further impact the YMDD loop changes on the ETV-TP binding-pocket.
It is well known that binding of miRNAs with their targets is strongly affected by the nucleotides in the 5' end of the miRNA MRE duplex[53], [59], and that, in contrast to the strict requirement for base pairing at the proximal region, nucleotide mismatch at the distal region seems to be highly tolerated.
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Prince's prescription opioid addiction was enabled by his wealth, but he wasn't alone: opioids are a major cause of premature death in America, killing 20,000 people per year, used by over four million Americans despite being highly addictive, tolerated largely because they are a very big, very profitable business.
MA.17 has demonstrated that letrozole is highly effective and extremely well tolerated when given in the extended adjuvant setting.
Triptans have shown to be highly effective, well tolerated and the most cost-effective migraine therapy in patients with severe symptoms and disability [14].
The design of intelligent, stimuli responsive nanosystems promises to expand diagnostic and therapeutic options in medicine by making available an array of highly effective, well tolerated platforms that go beyond simple delivery of drugs or imaging agents.
Conclusions: Omeprazole is well tolerated, highly effective, and safe for treatment of erosive esophagitis and symptoms of gastroesophageal reflux in children, including children in whom antireflux surgery or other medical therapy has failed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com