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For example, epileptiform discharges are associated with bursts of neural ensembles with highly synchronized activity [14].
In the absence of PNU-120596, the mean open time of hippocampal α7* nAChRs is very short (∼100 µs, [54]) and therefore, only a highly synchronized activity of α7* nAChRs can be confidently detected in voltage-clamp whole-cell experiments.
Strikingly, we found that in the absence of noise epochs with highly synchronized activity were found for almost all combinations of gE and gI, whereas these seizure-like events were absent in simulations where noise was present.
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Within the first 30 seconds after the heart had stopped, all the mammals displayed a surge of highly synchronized brain activity that had features associated with consciousness and visual activation.
In humans, similar observations have been made [6] where highly synchronized EEG activity occurs in response to stimulus input.
Structural and functional connectivity are highly related, with regions showing dense white matter connections being likely to exhibit highly synchronized brain activity (high functional connectivity) (van den Heuvel et al., 2009).
More recently, neurons in monkey GP demonstrated synchronized activity with saccadic generation (Shin and Sommer, 2010).
As a function of time, SD reflects the dynamics of synchronized activity within a region of interest.
The core reactions conforms a single cluster of permanently connected metabolic processes where the activity is highly synchronized representing the main integrators of metabolic activity.
Hence, even during periods of elevated background activity, highly synchronized input will effectively trigger postsynaptic spikes at high temporal precision.
We found that the activities were highly synchronized between the direct and indirect pathways within one hemisphere and were desynchronized between the two hemispheres.
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