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The book's subtitle is highly problematical (just as Empire's was: "How Britain Made the Modern World", for goodness sake).
One or two scholars said it was barely possible President Clinton could mediate, but most argued that his long working relationship with Mr. Gore and the deep suspicions that he still engenders in parts of the electorate made any such role highly problematical.
Specifically, the book shows the category of the "Indian Muslim," upon which the state of Pakistan was founded, to be highly problematical, loosely knitting together a wide range of competing and contested interest groups.
The Quaker situation was becoming highly problematical for the magistrates.
However, as with the potential pancreatic effects described above, drawing conclusions from spontaneous reports is highly problematical.
In contrast, although pure chemicals are used in Western medicine, which then avoids this type of problem along with antagonistic or undesired (non-intended) side affects, their effects are acute and side effects, especially the selection for chemoresistant cancers and antibiotic-resistant bacteria, are still highly problematical.
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This carrot-and-stick policy is extremely problematical.
Any of the miRNAs processed from the Sfmbt2 primary transcript would be imprinted, although testing this is problematical given the highly repetitive nature of the array itself, and the presence of other family members at other locations in the genome.
"For any non-derivative method, the issue of termination is problematical as well as highly sensitive to problem scaling.
(Perhaps he has a weakness for chintz.) His informed contempt is highly entertaining, but he neglects some of the more problematical and perhaps more illuminating aspects of his story, like Dean's reasons for reinventing himself and what he might be feeling as he does so.
Other ideas are more problematical.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com