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Stated another way, colon CSCs with high Wnt expression were highly potent at inducing tumors following injection into mice.
HMG-CoA reductase inhibitors are highly potent at lowering LDL cholesterol.
Dendritic cells (DCs) are professional antigen presenting cells that are highly potent at initiating and regulating immune response to control infection.
21 On a per parasite basis, P. vivax is highly potent at inducing pro-inflammatory cytokines, such as TNF 21, 120, 121, 123, 124 and has a much lower pyrogenic threshold than P. falciparum (180 vivax parasites/μL compared with 1,000 falciparum parasites/μL).
All three of the novel E7-targeting siRNAs (E7 653, E7 141 and E7 127) were highly potent at depleting E7 and E6 RNA and protein, particularly at 48 h, which was therefore chosen as the time point to assess OTEs.
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Preliminary bioassays showed most analogues exhibited good insecticidal activities at 100 mg/L, and compound 1d and 2a were highly potent even at 10 mg/L.
The fluorescent agonist BY630-X- D -A- D -A-G-ABEA was found to BY630-X- D -A- D -A-G-ABEA at the adenosine A3 receptor in BY630-X- D -A- D -A-G-ABEA= 8.48 ± 0.09) and internalization assays (pEC50 = 7.47 ± 0.11).
This is the case where U.S. National Guard troops from Indiana, Oregon, South Carolina, and West Virginia were exposed to sodium dichromate, a known and highly potent carcinogen at the Qarmat Ali water treatment facility in Iraq.
ACET is a highly potent antagonist at GluK1-containing KARs (Dargan et al., 2009) and has weaker activity at some GluK3-containing KARs (Perrais et al., 2009).
Researchers have recently found several dozen broadly neutralizing antibodies (bNAbs) that are highly potent and work at low doses.
GRK3 and GRK3ct were highly potent and efficient at the endothelin receptors (IC 50) for GRK3, 5 +/- 0.7 pmol/mg of protein; EC 50) for GRK3ct, 2 +/- 0.2 pmol/mg of protein).
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CEO of Professional Science Editing for Scientists @ prosciediting.com