The phrase 'highly population' is not correct or usable in written English.
The correct phrase is 'highly populated'. Example: The city is highly populated due to its growing job market.
The justification of utilizing a greedy selection algorithm is that genes that are part of more highly population motifs have been hypothesized to be more important as compared to genes which are part of more sparely populated motifs [29].
The relevance of an item can be highly population specific.
The number of highly population differentiated SNPs among all 1,000 randomized SNP sets was compared to the number of highly population differentiated SNPs among the sets of independent cis-eQTL using the Mann–Whitney test.
The occurrence of CpG-SNPs and their effect on allele-specific methylation regions is highly population and cell-type specific.
This is mainly beneficial for the imputation of rare variants, which have probably arisen recently and are highly population specific.
In addition to being copy number variable, this locus is highly population stratified and the presence of extreme levels of sequence duplication can complicate assay design.
Finally, the results of the present study support our previous thesis that the host determinants of HIV pathogenesis are likely to be highly population-specific [34], [36].
Thus, we caution that as the genetic information was derived from European and African American HIV-positive subjects and because host-virus interactions are likely to be highly population-specific, the composition of the GRGs might vary depending on the study population.
The structure of LD can be locus specific due to varied recombination and mutation rates or natural selection pressure, but is also highly population-specific [ 14].
Network analysis was done using R with disease network visualization performed with Gephi software [ 83]. miRNA: microRNAs; PD-miRNA: Population-differentiated miRNA; HPD-miRNA: Highly population-differentiated miRNA; mRNA: Messenger RNA; SNP: Single nucleotide polymorphism; indels: Insertions and deletions.
The degree of LD, which is highly population-specific [ 43, 44] and locus-specific [ 45], will determine the resolution of an association study, thus influencing the choice between CG or GWA strategies.
