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In the present work, we demonstrated that cellular resistance to TMZ was highly overcome by BSO, whereas NAC prevented TMZ cytotoxicity.
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The use of eco-friendly inorganic geopolymeric matrices, alternative to the polymeric resins, would be highly desirable to overcome these issues.
The use of a fire resistant inorganic resin, as geopolymers, instead of polymeric resins, would be highly desirable to overcome this issue.
Therefore, the use of phages as an alternative treatment came under the spotlight again because the phage is highly specific, can overcome antibiotic resistant bacteria and are available in large quantities in nature.
Formulating RIF is highly desirable to overcome the adverse side effects associated with systemic distribution (43, 51, 52).
Development of novel antitumoural strategies is therefore highly desired to overcome resistance mechanisms and to prevent tumour progression.
This is probably because, in the absence of repression, the metE gene is very highly expressed to overcome the fact that it is such an inefficient enzyme [ 16].
Availability of an unlimited source of transplantable insulin-producing cells is highly desirable to overcome the current inadequate supply of human pancreatic islet cells for transplantation.
Thus alternative neutralizing agents are highly desired to overcome the economic and ecological hurdles of the calcium carbonate neutralization during large-scale lactic acid production [ 3].
Apparently, such "sparse" SMG parameters can hardly represent the continuous muscle behaviors, and it is highly desirable to overcome the technical difficulty of automatically extracting continuous SMG patterns prior to the comparisons between SMG and EMG/MMG.
Currently pretreatment technology cannot effectively overcome highly recalcitrant material such as forest biomass, in which physical and chemical barriers such as lignin are hard to remove without a significant amount of energy input [ 1, 2].
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Justyna Jupowicz-Kozak
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