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But mixing recognition-based and question-based enquiries is unwise, because the former is highly leading: if an image depicting unilateral headache is recognized, it cannot be followed by the question "Is your headache on one or both sides?" [27].
Conversely, the amplification procedure may alter the apparent transcript abundance as some sequences may amplify highly leading to over-representation in AS, which may increase their candidate transcript counts above the noise threshold.
In embryonic stem cells Lin28 expression is highly leading to the inhibition of let-7 microRNAs processing steps.
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Tea grown in the Darjeeling region of India is highly prized, leading many to call it "the champagne of teas".
With all of this deliberate silliness, "The 39 Steps" could easily be a comic success without a highly skilled leading man.
The flat-rate poll tax proved highly unpopular, leading to large-scale demonstrations and the worst riot in the city of London in the 20th century.
This process is highly reversible leading to high capacity retention.
Many customer accounts were highly leveraged, leading to big losses for investors as well.
In agrarian economies, the ownership of capital was highly concentrated leading to significant inequalities of wealth and income.
In addition, human cytochrome P450 genes are highly polymorphic, leading to inter-individual differences in drug metabolism [20].
Interpretation of TRUS images is highly subjective, leading to difficulties in target, OAR, and source identification during implantation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com