In fact, I'm still a highly inactive member of the party, which makes me as naive as those I criticise.
At present, the older adult population is highly inactive [ 4, 5].
In contrast, we showed a significant colocalization between H3K9me3 and H2A.Z on rDNA cistron during winter, a season in which rRNA transcription and processing are highly inactive.
This was based partly on results from imaging studies, which showed that brain regions including the frontal cortex and the thalamus were highly active when the patient was on zolpidem and highly inactive when she was not (Brefel-Courbon et al., 2007).
The chaperonin cochaperonin interaction in these single-ring systems was weaker, by at least a 50-fold reduction, than the highly stable inactive GroELSR GroES.
When used as a neonatal prognostic tool, EEG background activity is classified as normal, abnormal (type A and type B discontinuous and hyperactive rapid tracing) or highly abnormal (inactive, paroxysmal, low voltage plus theta tracing).
Members of our group have shown that maspin is not functional as a serine protease inhibitor (Bass et al, 2002), which has now been confirmed at the structural level (Al Ayyoubi et al, 2004), where it has been shown that the reactive centre loop necessary for inhibitory function is maintained in a highly constrained, inactive conformation.
These risk factors were: cigarette smoking (never smokers, former smokers, current smokers); alcohol consumption (males: abstainers, 0 39 g, 40 59 g, 60+ g, and binge; females: abstainers, 0 19 g, 20 39 g, 40+ g and binge); and physical inactivity (highly active, active, insufficient, inactive).
Structural studies have shown that the conformation adopted by kinases in their active state is highly similar, whereas inactive kinases can adopt a variety of conformations.
The X and Y chromosomes typically join at their pseudoautosomal regions to form a highly condensed and inactive XY body during the pachytene stage of meiosis (Fig. 1A).
For the study of chemotactic signal transduction the spermatozoon is a limited cellular model since it is believed to be a highly differentiated transcriptionally inactive cell, where most of the molecular approaches cannot be applied (e.g. transfection, protein over expression, etc).
