The paucity of pharmacologic information regarding colistin administration in the critically ill highly impedes the creation of optimal dosing regimens that reconcile adequate antibacterial activity with minimal toxicity.
All these acids were totally removed by PEF, but the formation of small amounts of other highly recalcitrant products impeded the total mineralization.
The structure of these clusters is still highly uncertain, however, impeding the construction of quantitative models of soot inception and growth.
FIBCs are made of polypropylene woven fabric which as a highly insulating material impedes the dissipation of electrostatic charge, which has accumulated in the FIBC caused by the charged product.
Any serious debate about constitutional reform is impeded by the highly personalised nature of the system, and the deeply conservative attitudes toward reform that the monarchy encourages.
Dealing with new fiscal and investment issues can be tricky, especially when rational decision making may be impeded by the highly emotional state that most people find themselves in immediately after a divorce.
However, the spread of these beneficial resistance mutations is likely to be impeded in more highly spatially structured environments.
Alfalfa, one of the most important forage crops in the world, is autotetraploid, allogamous, and highly heterozygous, characteristics that have impeded the construction of a high-density linkage map using traditional genetic marker systems.
Similarly, this has been observed by Parte and colleagues [ 8] who experienced difficulty using DAPI staining of comparable small, round cells scraped from the human adult ovarian surface epithelium; they explained this by identifying a highly compacted nuclear chromatin which impeded staining.
Special interests resisted change, dysfunctional fragmentation impeded progress, and poor, highly needy groups dispersed in remote locations had to be reached.
