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The cancer methylome is highly disrupted, making DNA methylation an excellent target for anticancer therapies.
Generally, increasing the percentage of the directly-linked triptycene component increased chain rigidity, interchain spacing, and fractional free volume due to more highly disrupted chain packing.
It also appeared that a small population of the cells changed to unusual morphologies with macrophage-like processes and highly disrupted cytoskeleton.
"The fact that people were being highly disrupted in their travel plans was a concern, but at the same time a lot of these other triggers were not pulled.
The variant caller could not detect copy-number losses and gains reliably in FFPE samples because of the highly disrupted signal, and visual inspection was not possible due to the waviness of the Log2 ratio.
True restoration of highly disrupted native ecosystems is universally difficult, and has not been achieved on waste rock dumps at a rock phosphate mine in the resource-limited rangeland environment of semi-arid Queensland, Australia.
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Hence, climate change will highly disrupt the livelihood systems of large sections of the population who reside in the lowlands and highlands and will continue to suffer more from climate change in the future (World Bank 2010).
The results show that meander morphodynamics have been highly constrained and disrupted by engineering works, probably for over a century.
The City of London, and other commercial centres such as Glasgow, Norwich, and Newcastle, objected to the war because it disrupted highly profitable Anglo-American trade.
Further east (beyond the dome structure) between SP 2900 and 3600 on the same profile, the outerarc sediments from the Neogene to Present seabed are highly folded and disrupted by thrust faulting.
saw their highly choreographed lunch disrupted by advocates.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com