15– 17 Mental illnesses, which are highly disabling, rise in importance when disability is taken into account.
Bipolar disorder (BD) is a prevalent, chronic, severe, and highly disabling psychiatric disorder that is associated with increased morbidity and mortality due to general medical conditions.
We have shown, for the first time, that dyspnea can be a side effect of subthalamic nucleus deep brain stimulation, and that this dyspnea may be highly disabling.
Opioid use disorder is a highly disabling psychiatric disorder, and is associated with both significant functional disruption and risk for negative health outcomes such as infectious disease and fatal overdose.
Migraine and MOH are highly disabling.
Migraine, a highly disabling neurological disorder, is characterized by recurrent moderate to severe attacks associated with vegetative symptoms [1].
Highly disabling chronic pain is a frequent complaint in children, with consistent prevalence estimates of approximately five percent in Western countries [ 1].
Migraine and medication-overuse headache (MOH) are the major contributors [18, 19], being highly disabling at individual level; tension-type headache (TTH), while less disabling at this level, is the second most prevalent disorder in the world [17].
GAD commonly co-occurs with other anxiety disorders and/or depression and is highly disabling, resulting in levels of disability comparable to depression [3], [4].
Schizophrenia is a chronic and highly disabling mental illness that contributes 15.2 million Disability Adjusted Life Years to the burden of disease in low and middle income countries (LMIC) [ 1].
This difference remained similar after adjusting for all other variables (Table 5), with HCPs reporting highly disabling LBP estimated to have higher FABQ-physical scores than those reporting low disability (mean difference [95% CI]: 2.8 [1.5 - 4.1], p < 0.001).
