This makes it extremely difficult to assess the various merits of each scheme and even harder to assess their impacts.
In embryos lacking both βPS and βν midgut development was highly disrupted making it difficult to assess whether NetB and Fra localisations were completely normal.
Since antibody drugs are highly species specific, it is difficult to assess the immune response in humans when conducting preclinical animal experiments even with non-human primates.
However, since a model's parameter values are uncertain, and since dynamic responses to inputs are highly parameter-dependent, it is difficult to assess the confidence associated with these in silico predictions.
However, with two such highly correlated measures, it is difficult to assess whether body fatness at any one period is of importance, or whether they simply reflect the effects of one another.
Task performance is highly variable between individuals making it difficult to assess the impact of neck pain on small samples even with detailed motion analysis.
However, the former (physician charting) is difficult to assess, being highly variable and dependent on many factors not elucidated in administrative data, such as communication between physician and patient and the experience and expertise of the physician [ 14].
Although PGx-guided selection of warfarin dosage could be more cost-effective than alternative treatment with dabigatran, the impact of warfarin pharmacogenetics is difficult to assess due to highly variable effects caused by non-genetic factors such as diet.
In contrast to survival, objective response is more difficult to assess because it is highly dependent on the quality of radiological tumour measurements.
And it is difficult to assess independently, because the building includes highly desirable retail frontage, oddly shaped midrise floors and upper stories with such sweeping panoramas that they seem to be suspended in space.
