A total of 1,901 targets (1,371 unique targets) included 154 EST sequences of M. amblycephala were predicted for the 24 highly significant differently expressed miRNAs (P < 0.01), which were identified in this study.
Though highly homologous, different Ssa members affect yeast prions differently (Jung et al. 2000; Schwimmer and Masison 2002; Sharma and Masison 2008, 2011; Sharma et al. 2009a).
SGK-1 and AKT-1 two highly homologous kinases differently reacted to ceramide treatment, since SGK-1 increases in response to apoptotic stimulus while AKT-1 decreases.
We compared a recently constructed list of 65 candidate POAG genes (reviewed in [ 31]) with the genes that were highly and/or significantly differently expressed in the CPE and NPE.
A microsite allows for the creation of a highly targeted, sometimes differently-branded site that is focused on the exact needs of a specific audience.
The main conclusions of this paper — (i) different functional classes of genes evolve differently, (ii) highly expressed genes evolve slowly and (iii) fast evolving genes often evolve in a lineage-specific manner—have already been reported comprehensively by several groups (Gerstein, Siepel, Hurst, Koonin, Drummond, Nielsen, Bustamante and many other labs).
Interestingly, we observed (Table S1 and Figure 1C) that the AD samples and control samples were highly similar (only 11 differently expressed genes) in gene expression.
This situation, in which individual patients weigh possible benefits and harms of treatment differently, is highly suitable for shared decision making (Muller-Engelmann et al, 2011; Wong and Szumacher, 2012).
Second, the red lines in the four graphs of the figure (left column) which show the aggregate of papers in each field refer differently to highly-, medium-, and lowly-cited papers.
It is a highly variable disease affecting individuals differently.
