This is a highly complicated process covering a hugely diverse range of sometimes interconnected regulations.
Ribosome assembly is a highly complicated process that engages more than 200 protein assembly factors (AFs) and many snoRNAs (Woolford and Baserga, 2013).
Transcription of eukaryotic genes is a highly complicated process requiring the ultra-precise cooperation of a batch of interactions among functionally diversified proteins and DNA sequences (Maston et al. 2006).
Biological morphogenesis is a highly complicated process, involving genetic regulation, pattern formation, the biophysics of collective cell migration, mechanical cell-cell interactions, and so forth.
CCA is often associated with metastasis which is a highly complicated process that involves cell motility, invasion, angiogenesis, intravasation of tumor cells into the blood stream, and finally extravasation and colonization of tumor cells at secondary sites [ 2].
Wood formation is an essential but highly complicated biological process derived from plant secondary growth in woody plants.
One of the major challenges to this accomplishment is the need for optimization of cryoprotectant agent (CPA) perfusion procedures that involve highly complicated mass transfer processes in organs.
It must be emphasized, that our developed model is only a crude approximation of highly complicated ensemble of processes, associated with ER-mediated activation of transcriptional machinery.
Its biosynthesis is a highly complicated and multifaceted process involving at least 14 additional assembly factors.
The model is based on large-eddy simulation (LES) methodology in conjunction with detailed gas-phase chemical kinetics to accurately model the highly complicated combustion and nucleation processes in a turbulent flame.
