Exact(4)
The present results suggest that the larger 50 nm GNPs may be highly cleared via urine and bile.
WHAT THIS STUDY ADDS TO OUR KNOWLEDGE ☑ For drugs that are highly cleared via CYP3A4, a well-conducted pharmacologic inhibition study may reflect the worst-case scenario for changes in AUC in patients with severe HI.
There has been a level of consensus that the models are equally compatible with all but the most highly cleared drugs leading to pragmatic acceptance of the simplest of these, the well-stirred model (Ito and Houston 2005; Hallifax et al. 2010).
These analyses showed that, for drugs that are highly cleared via CYP3A4 (i.e., fm > 50%), a well-conducted pharmacologic inhibition study with a strong and specific inhibitor for CYP3A like ketoconazole may reflect the "worst-case scenario" for changes in AUC when enzyme activities are impaired by either DDI or OI.
Similar(56)
"It's a highly specialized area of interest," Mr. Brosterman said, stressing the word "highly," clearing his throat, and giving a facetious grin to his client and friend Mark Chiarello, a wax museum enthusiast.
As I say, the jury is out on that and it is still not highly clear to me how the UK gets from where it is now to having a clear consistent plan by the end of March".
Result: The 3DX produced highly clear, three-dimensional tomographic images of impacted teeth.
The highly clear crystal lattice as well as the corresponding well-ordered dot pattern of the fast Fourier transform (FFT) image demonstrates the high-quality single-crystalline nature of Mn3O4.
Significant activation in the left inferior frontal gyrus was not observed only in the b/n task, probably because articulatory contrast between /b/ and /n/ sounds was highly clear for Japanese speakers.
In this paper, we reported a new technique for the preparation of a highly clear and transparent emulsified aqueous solution containing immiscible monomer (3,4-ethylenedioxythiophene, EDOT) droplets with diameters of a few tens of nanometers under surfactant-free conditions using tandem acoustic emulsification.
Especially in EAS, such trend was highly clear (nominal P = 0.027, 0.018, 5 x 10− and 0.014, FDR corrected P = 0.063, 0.051, 0.004 and 0.048 for SPL of 1 4 respectively), similar to the pattern in the main figure 3 B.
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