In addition, the importance of studying full-length Bcl-2 proteins in their native environments was highlighted by the altered binding specificity of Bid chimeras to truncated prosurvival proteins.
There were differences, however, in that more amino acid related subsystems were significantly affected in the anaerobic case (Table 4), further highlighting that altered ammonium assimilation in the mutant has a more widespread effect under anaerobic conditions.
These findings, along with the findings reported here, highlight the relevance of altered Ca2+ homeostasis and signaling in SCLC.
These measurements highlight the effect of altering the molecular weight (Mw) of PTMO, which is used as a soft segment (SS), on the microstructure.
Our results emphasize the relevance of the laforin malin complex in the control of glycogen metabolism and highlight altered glycogen accumulation as a key contributor to neurodegeneration in LD.
Investigations about the biological meaning of our 793 probes signature highlighted significantly altered proliferation pathways, suggesting that the exposed normal tissues exhibit a proliferation signal in their transcriptome.
Additional intriguing dimensions to the recognized promiscuity of QacR-multidrug interactions are highlighted by the significantly altered binding position of Et in the QacR(E90Q -Et complE90Q -Ethe two distincomplexbinding sites found in the structure of Qand(E90Q)-R6G.
These varying lines of evidence highlight altered cross-talk between epithelial and mesenchymal cells, mediated by FGF/FGFR signaling and causing palate malformations.
Level settings (shadow and highlight only) were altered where necessary to avoid any change or loss in cellular detail relative to what was observed in the microscope; changes were applied uniformly to the image presented and were similar from one image to another.
By enabling the simultaneous monitoring of a large set of metabolites in cirrhotic patients with HE, CSF metabolomics highlighted several altered metabolite pathways linked to ammonia metabolism, neurotransmission and energy metabolism.
