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The CC50 of calcium folinate, 2-aminobenzenesulfonamide and midodrine could not be determined since none of these molecules was cytotoxic at the highest tested dose.
The patterns of vitamin C and trolox had not evidenced cytotoxicity at the highest tested dose.
Hence, in all subsequent experiments we used metformin at 800 mg/kg diet, which is the 80% of the highest tested dose.
Since mortality rates remain zero after being treated with highest tested dose, MTD of P ECA-IA-MEG) hydrogel was higher than 10000 mg/kg body weight by oral administration for BALB/c mice.
In contrast, when the 3 were combined with the plant to form GZ17, the cell death rate was greatly enhanced to the point that nearly all cells were dead at the highest tested dose.
In cancer cells, and in particular in HT-1080, ROS production was higher than in normal fibroblasts and increased with NP concentration at least up to the highest tested dose.
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However, in the presence of S9, a mutagenic effect is observed with all the tested extracts, in the presence of S. typhimurium TA98 strain, at the two highest tested doses, and only with aqueous extract at the highest tested dose in the S. typhimurium TA 102 assay system.
Testing of the drug, zenarestat, was halted after the company found that in a small number of patients the drug was potentially toxic to the kidney at the highest tested dosing, Pfizer said.
From the obtained dose response curves, it is obvious that the ACh-induced vasodilatation was saturated for the highest tested doses.
The highest suppression was recorded for A. integrifolia at the highest test dose of 800 mg/kg/day.
Therefore, it was decided to take 250 μg/kg TNF- α as the highest test dose for all experiments and to repeat the OFT with a vehicle and 125 μg/kg TNF- α group.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com