Testing of the drug, zenarestat, was halted after the company found that in a small number of patients the drug was potentially toxic to the kidney at the highest tested dosing, Pfizer said.
bRecommended for use in environmental risk assessments of pharmaceuticals (EMA, 2006); cThe highest tested concentration.
In fact, lethal effects only occurred at the highest tested concentration.
Consequently, high thrust was measured at both the lowest and highest tested Strouhal numbers.
In ABTS free radicals scavenging assay compound 1 exhibited 88.51 ± 0.62 % inhibition at highest tested concentration i.e., 1000 μg/mL.
The dose was the highest tested, and it also represented the maximum dose of CFU per milliliter producing viable bacteria.
However, in 3 mm of deflection, which was the highest tested, the CB showed higher forces than the SLB.
For all the inhibitors, the inhibition efficiency increased with increasing concentration, reaching a maximum at the highest tested concentration.
For this viral transcript the linear dynamic range spanned from ten copies to one million copies (highest tested).
Highest tested concentration of arsenite (20 ppm) was found to be detrimental in both IEC and IEC-6.
After that, the friction factor starts to increase sharply when Reynolds number is over 2000, and it keeps increasing until the highest tested Reynolds number.
