Sentence examples for highest synergy from inspiring English sources

Drugs demonstrating the highest synergy were selected as leads and tested in different prostate and pancreatic cancer cell lines, and one immortalized human pancreatic epithelial cell line.

An unbiased RNAi screen for enhancers of dalotuzumab efficacy revealed that blockage of the PI3K/AKT/mTOR pathway achieved the highest synergy, and thus drugs targeting this pathway were the strongest candidates for combination therapy (Di Cosimo et al, 2010).

These experiments were performed using the two cell lines that exhibited the highest synergy and in BxPC3 cells, a commercially available cell line previously reported to be capable of forming tumorspheres [ 35, 36] that also exhibited a potent synergy (Additional file 1: Figure S1).

We did an exhaustive search through all gene pairs in a publicly available prostate cancer data set, identifying the gene pairs with highest synergy and validated our results by confirming that their P values are extremely small and hypothesized on their biological interpretation.

The Pvalue of the maximum synergy x0 found in the actual data (defined, in this case, as the estimated probability of obtaining maximum synergy at least as high as x0 by pure chance when the null model includes the highest synergy values among N = (12, 625 2 ) = ~80 million gene pairs for each permutation experiment) was then evaluated as 1- F(x0).

More specifically, I have found that people who share the values of humility, honesty, trust, and discipline achieve the highest synergies.

For this purpose, we did 100 permutation experiments of each type, saving the corresponding 100 highest synergies after doing exhaustive search in each permutation experiment.

The L05S10 generated high synergy in shear resistance whereas the L10S05 did little.

The assumption of vulnerability as a precursor for pursuing synergy was supported by the fact that small island states possessed relatively high synergy potential.

Mechanical properties of ternary composites demonstrated high synergy between fillers, leading to manifold increase in the modulus of dual filler filled composites in comparison to single filler systems.

The use of independent pooled samples with significantly higher numbers of cells may have generated a more robust set of proteomic data and showed a higher synergy between the transcriptome and microarray analyses of these cells.