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Up to five lesions (defined as the five with the highest standardised uptake value (SUV)) from any single patient were considered.
The uptakes were quantified by measurements of the highest standardised uptake value - maximum pixel activity in correlation to body weight and the injected dose, grams per millilitre (standardised uptake value (SUVmax)).
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Positron emission tomography (PET) with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose 2-[fluorine-18]-fluoro-2-deoxy-D-glucose 2-[fluorine-18]-fluoro-2-deoxy-D-glucose 2-[fluorine-18]-fluoro-2-deoxy-D-glucose 2-[fluorine-18]-fluoro-2-deoxy-D-glucose 2-[fluorine-18]-fluoro-2-deoxy-D-glucose 2-[fluorine-18]-fluoro-2-deoxy-D-glucose 2-[fluorine-18]-fluoro-2-deoxy-D-glucose
In 25 sarcomas there was a high correlation (ρ=0.83) between a semi-quantitative measure of FDG retention (the standardised uptake value or SUV) and NCI grade.
Lesions were considered PET-positive if their standardised uptake value (SUV; corrected for body weight and height) was distinctively higher than the surrounding background activity.
The maximum standardised uptake value (SUVmax) within this region of interest was calculated, and standardised according to body weight, dose of administered FDG and time to imaging.
The high variability in binding observed using this method has motivated the use of simplified ratio-based approaches such as standardised uptake value ratios (SUVRs) and distribution volume (VT) ratios (DVRs); however, the reliability of these measures and their relationship to VT have not been sufficiently evaluated.
Studies using semi-quantitative measures such as standardised uptake value (SUV) or differential uptake ratio (DUR) have demonstrated that aggressive lymphomas tend to have higher FDG uptake than indolent histologies.
Studies using semiquantitative measures such as standardised uptake value (SUV) or differential uptake ratio (DUR) have demonstrated that aggressive lymphomas tend to have higher FDG uptake than indolent histologies.
Background and objective: Standardised Uptake Value (SUV), in clinical research and practice, is a marker of tumour avidity in Positron Emission Tomography/Computed Tomography (PET/CT).
Uptake is shown as a standardised uptake value (SUV).
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