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Discover LudwigThe phrase "highest single dose" is grammatically correct and can be used in written English
It usually refers to the highest amount of a medication that can be taken at once. Example: The recommended treatment for this illness is to take the highest single dose of the prescribed medication.
Exact(1)
One patient experienced an infusion reaction at the highest single dose, while another developed neutralizing antibodies to LymphoStat-B.
Similar(59)
We have shown in previous studies that both fractionated irradiation and high single dose irradiation to the carotid arteries accelerate the development of atherosclerosis in apolipoprotein E-deficient (ApoE−/−) mice and predispose to the formation of an inflammatory, prothrombotic plaque phenotype [7], [8].
It is minimally toxic at a high single dose.
IORT implies delivery of a high, single dose of radiation to a limited intrasurgical anatomic area.
The mice were orally treated for 5 days; then a high single dose of MnCl2 (100 mg/kg) was given by intraperitoneal injection to the mice.
In fact, experimental diabetes during pregnancy, induced by a high single dose of streptozotocin, occurs by direct toxic effects on pancreatic β-islet cells [ 23].
STZ when administered at a high single dose induces diabetes by the direct toxic effects on pancreatic β-islet cells [ 23].
One of the interesting candidates from the previous study, SNCG, was markedly increased by a high single dose of 10 Gy but not by fractionated irradiation.
Regimens employing a higher single dose of rectal artesunate were five times as likely to result in >90% parasite reductions at 24 hours than were multiple lower doses of rectal artesunate or than a single administration of artemether.
Considering the increased biological effectiveness of a high single dose [ 26], total doses which are equivalent to 60-70 Gy in conventional fractionation can be achieved using an IORT boost in combination with moderate doses of external beam radiation therapy [ 27].
This radiation if applied as high single dose fraction, in most of cases of photons, is defined as radiosurgery (RS), also named by many authors as stereotactic radiosurgery (SRS).
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