This was also observed for apoptosis (except for a slightly higher sensitization by CHX in Pt45P1 cells), underscoring the potential of HHT as a sensitizer also for apoptotic therapy regimens and in agreement with a previous study [ 30].
The higher sensitization for thermal annealing on TL mechanism in the region 550 600 °C for 80(TeO2)–5(TiO2)–(15 − x) (WO3)–(x) AnOm where AnOm = Nb2O5, Nd2O3, Er2O3 and x = 5 mol% has been measured.
Other possibility is that higher chronicity (history with pain symptoms) of headache can also explain higher sensitization levels [32].
We also observed that the group of patients with TTH with higher sensitization levels also exhibited a longer history of headache, supporting this hypothesis.
This study identified a subgroup of patients with TTH with higher sensitization, higher chronicity of headaches and worse quality of life but lower frequency and duration of headache episodes.
It appears that among the clinical features of headache, the frequency of attacks is the most relevant outcome since higher frequency of attacks is associated with higher sensitization [6].
Many plants are generally known for their ingredients of high sensitization potential [2], such as Achillea millefolium, Arachis hypogaea, Arnica montana, Ginkgo biloba, Glycine max, Helianthus annuus, Inula helenium, and Ricinus communis.
Nevertheless, the presence of higher sensitization in patients with lower frequency of headaches is contrary to what is observed in patients with migraine and co-morbid fibromyalgia syndrome since a higher frequency of migraine attacks enhances both hyperalgesia and widespread pain symptoms [29].
We found that Gal d 1 and Gal d 2 are generally major egg allergens, whereas Gal d 3 5 displayed high sensitization prevalence only in patients reacting to both, egg white and yolk.
Many people have high sensitization rates to a variety of allergens, but some do not develop AR.
Overall, the evidence reviewed here suggests that blood transfusions can lead to high sensitization and negate the benefits of transplantation, therefore they should not be encouraged as first-line therapy of anemia.
