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Picking the protein scaffold with highest scaffolding power ensures that contigs mapping to multiple orthologous proteins are scaffolded together by the ortholog that has the highest scaffolding power.
Once the scaffolding power of each protein is computed, the protein scaffold with the highest scaffolding power is iteratively picked, and the maximal scaffoldable sets (and scaffolding power) of all other proteins are updated so that a contig gene model (the contig region) is only used once.
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In SWiPS, the implementation of these ideas is summarized by the definition of two concepts, the scaffolding power and the maximal scaffoldable set, which are described next.
After all guide proteins above a minimum scaffolding power have been chosen, the scaffolded contigs go through another scaffolding phase in which contigs with multiple gene models are used to merge the scaffolds together.
All paths having scores with at least β (default β = 0.5) times the highest scoring path are then compared, and contigs present in all higher scoring paths are kept and form a maximal scaffoldable set, with a score referred to as the scaffolding power.
Behind a high scaffolding hung with a massive Rolex billboard, grinding power tools herald the construction of a Four Seasons hotel.
Contemporary illustrations show cathedral spires collapsing, vaults caving in, high scaffolding keeling over in a chaos of planks and poles.
Vast concrete blocks weigh down a six-metre-high scaffolding structure on Eastcheap in the City of London, swathed with lengths of green and black netting.
Use caution when working from high scaffolding or in elevated positions.
You're higher than that high power.
dictators had the highest level of power.
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