The ICCs computed per genotype showed that the PER3 5/5 [ICC (95% CI =0.72 (0.88, 0.88), n=11 subjects, 4.0 replicates/subject on average] and PER3 4/5 [ICC=0.87 (0.33, 0.87), n=8, 3.8 replicates on average] had a higher replicability of repeated measurements per individual compared to the PER3 4/4 genotype [ICC=0.42 (0.73, 0.73), n=13, 3.2 replicates on average].
Indeed, if monomers are still available relatively far from where they were produced (i.e., far from the sites of enzymatically active replicators) then parasites can make use of their higher replicability R due to loose folding (small pfold – check Eq. 5), and thereby take over in most localities.
A high replicability in region-of-interest (ROI) morphometric or ROI-based connectivity analyses is essential for such methods to provide biomarkers of good health or disease.
It resulted in a total of 43 jointly high scoring genes out of 100 top-ranked genes associated with IPD – implying a relatively high replicability of results across datasets.
A recent study showed high replicability of results from Europeans-based GWA studies in Asians; however, population-specific loci may exist due to distinct linkage disequilibrium patterns.
In addition, due to their high replicability over time, automated methods might have an advantage over manual tracing in longitudinal analyses.
Each of these factors leads to straightforward predictions on where misconduct is most likely to occur (e.g., in fields where competition is high, replicability is low, conflicts of interest are high, etc)., which very few studies to date have verified empirically.
2, 63 Another advantage is the lower cost and higher replicability of genotyping compared with other cardiovascular risk factors.
Notably, however, high replicability observed here might have been aided by diluting the initial concentrated DNA sample, and potential inhibitors, to obtain 'low input DNA' samples.
In all populations, high replicability genes presented increased levels of high-frequency derived SNPs (derived allele with an allele frequency >50%).
