Sentence examples for highest reactivation from inspiring English sources

Among the cyclic tetrapeptide group, Apicidin at 1 µM exhibited the highest reactivation of viral production (Figure 1C).

To determine whether Cbx3 and Mpp8, the H3K9me3 readers which showed the highest reactivation of the LTR reporters, are required for silencing of ERVs, we performed qRT-PCR on cDNA isolated from wt TT2 and siRNA-treated mESCs.

It was therefore hypothesized that an extra contribution in affinity may be achieved by covalently connecting a peripheral site ligand (PSL) to a non-ionic reactivator, which may result in a higher reactivation potency of the total construct.

At the Lindau Test Site, application of a slip- and dilation tendency analysis on the resulting fault pattern reveals the high reactivation potentials for the N S striking ore dike as strike-slip fault and for NW SE striking structures as normal faults within the ambient stress field (see below).

A higher reactivation of these probe sets was observed with the combination of 5-aza-dC and TSA (Figure S1).

The S11 tumour cell line has been used to define some aspects of MuHV-4 latency [5] but again shows high reactivation rates and offers no way to compare recombinant viruses with the wild-type or uninfected controls.

Multiple lines of evidence support that methylation is important to maintain XCI including the reactivation of human X-linked genes upon treatment with DNA methyltransferase inhibitors (Venolia et al. 1982) and the high reactivation frequency for X-linked genes from the hypomethylated marsupial Xi during cell culture (Loebel and Johnston 1996; Kaslow and Migeon 1987; Rens et al. 2010).

The differences observed in the catalytic activity of Pt hkl) and Pd hkl) domains, such as the much higher CO-tolerance and the higher reactivation ability of Pd compared to Pt, as well as the differences between particular crystallographic orientations, were rationalized by DFT calculations and kinetic reaction modeling.

To find the best performing dose for each drug in each of the different regimens for each of the tests at different doses above we asked which gave the highest HIV reactivation whilst maintaining apoptosis below 20%.

High level reactivation ablates MuHV-4 persistence in vivo [39], so gammaherpesviruses have presumably evolved multiple levels of regulation to guard against this.

As expected, data show a high CMV reactivation rate in patients with burns, from 55%% to 71%% [ 3, 4].