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The highest rates of change were found in two teleost fishes, the stickleback and zebrafish, with the stickleback lineage experiencing the highest number of changes (603 gains and 126 losses after it split from the zebrafish lineage) recorded in any vertebrate lineage (Fig. 2a).
The smartIES project (H + S type) scored the highest number of changes (4353 changes) and revisions (120 revisions) while the group only committed 96 files.
Nonetheless, this is not always the case since in our example the team that has the highest Gini coefficient – indicating asymmetrical activity – also has the highest number of changes (smartIES).
The highest number of changes has been found in the HVR1, where most HCV antigenic sites have been reported [42], [43].
Figure 1 shows that macrophages responded to live P. gingivalis with the highest number of changes (677) in gene expression, although exposure to individual components also induced significant changes: LPS (575) and FimA (419).
Unsurprisingly, presence of both etiological factors led to the highest number of changes (716 genes altered).
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Merism has the highest number of state changes, due to the high number of changes from ancestral pentamery to non-pentamery in the large Pentapetalae clade.
Only for Patos Lagoon the analyses show a significantly higher number of changes for the Ba Ca ratio (H = 9.1, p = 0.03).
A high number of changes is produced also by removing "Spatial and temporal design" macro-criterion, but the entity of modification to the ranking is less deep.
The high number of changes and revisions in combination with the low number of committed files might be an indication that the members of the smartIES group were well-coordinated and they managed to perform the necessary edits and changes on the shared resources.
This shows that a disproportionately higher number of changes occur at synonymous sites than expected by chance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com