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Multiplicity analysis of somatic mutations could identify those with the highest multiplicity as those most likely to be effective molecular targets across multiple tumor types.
The basic concept of the Brewer Engel valence-bond theory that relates the electronic state of highest multiplicity which corresponds to the electronic configuration of lowest energy level or the structure of atoms, and corresponding phase structure both in individual metallic and multicomponent intermetallic systems, is also given.
This cluster contains the greatest number of known causal genes and has the highest multiplicity values.
In addition, of the top 20 highest multiplicity sequences in round 3, between a quarter and a half of them were also among the top 20 highest multiplicity sequences in round 5 for hHSF2 and hHSF1.
In round 3, the top 20 highest multiplicity sequences for each protein represented only ∼0.04% of the total pool.
For hHSF1 and hHSF2, the sequences from round 5 with the highest multiplicity values also had high interround enrichments.
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Given the four (or fewer) possible continuations of a k-mer, Rcorrector calculates a value equal to the ratio between the second highest and the highest multiplicities.
These reduced-homology PCLs allowed for the use of a novel high multiplicity of transduction ("high m.o.t").o.t
Parameter regions of higher multiplicity were also observed in some systems.
In this paper we extend the results to the multivariable case of higher multiplicity.
The Time Projection Chamber of the ALICE experiment is a large 3-dimensional tracking device for ultra-high multiplicity events.
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