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The cost increased by 15% when patient suffered from moderately severe stroke and further increased by 52% in the highest level of severity compared to mild stroke (p < 0.05).
The patients were predominantly older individuals with long-standing RLS; 19 of them scored at the highest level of severity on the Johns Hopkins Restless Legs Severity Scale (JHRLSS).
In case of discrepancy between mMRC and CAT results, the highest level of severity was chosen.
The reference value for gender was male, the reference population for brain disorders was stroke, and the reference value for disease severity was the highest level of severity.
When the multiple modified-NYU codes or CPT codes were not concordant, we selected the codes reflecting the highest level of severity or intensity to define the episode.
However, some tools had 'severe' or 'harmful' as the highest level of severity and did not have a separate category for life-threatening errors.
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Thus there was no indication that patients at the highest levels of severity showed different effects to the overall trend.
Continuous intravenous administration of inotropic agents is a hallmark of the 3 highest levels of severity, currently including 80% of the patients on mechanical circulatory support [ 20].
The incremental factor observed for the average e-GST in the highest levels of severity and activity is given in Figure 2e and is ∼130% while the incremental factor of e-CAT is <20%.
For projects which had a higher level of severity of problem factors, the influence on software maintainability becomes more obvious.
Recent data suggest that a greater age and a high level of severity of illness are predictive of poor outcomes.
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