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A study comparing active and passive recruitment found that active recruitment, i.e. paediatrician referral and direct mail, produced the highest inclusion rate [ 14], but a variety of obstacles to the active recruitment of children and their parents have been reported [ 15].
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We also noted a high inclusion rate of exons 8, 11 and 13 within CD44 from 4T1-derived tumors compared to 168FARN and 4T07-derived tumors.
We expect that the use of the conventional design will lead to a higher inclusion rate.
Our results with a high inclusion rate (866 patients over 2 months) and 21% positive urine samples compares favourably.
The review will only include those with a high inclusion rate so that the results are generalisable and will only include studies using validated quality of life measures.
In this study, the high inclusion rate involving 71% of patients indicated that the implementation of a geriatric assessment was very feasible.
As he was responsible for making contact with the families, his efforts contributed to the relatively high inclusion rate of children.
The study has a large sample size (>5,000 patients), a high inclusion rate, and a focused primary end point (1-month all-cause mortality).
If particular characteristics were associated with the non-inclusion status, our estimates of associations could be distorted, however, the relatively high inclusion rate of 83.8% makes a strong influence of missing cases improbable.
Although the size of study sample may seem limited, the quality of data, the high inclusion rate and the thorough BRCA screening that was performed justifies certain conclusions to be drawn from the dataset.
As our study was performed in standard medical practice, with a high inclusion rate of 67% resulting in a patient profile typical for early RA, our results are clinically relevant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com