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It turned out that the portfolio with the highest expected return on investment represented a significant departure from the status quo.
Suppose there isn't any pure-strategy deviation that's profitable, then there can't be any mixed strategy deviation that's profitable, because the highest expected return you could ever get from a mixed strategy, is one of the pure strategies in the mix, and you've already checked that none of those are profitable.
The carrot that the Global Market Portfolio dangles is the highest expected return for the least expected risk on a forward-looking basis.
Among many other things, in his work, Markowitz defined the concept of the "efficient frontier:" the set of all portfolios that will give the highest expected return for each given level of risk.
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One of the researchers, Dr Ramon Luengo-Fernandez, from the Health Economics Research Centre at the University of Oxford, said: "By estimating the economic burden of several diseases it will be possible to help allocate public research funding towards the diseases with the highest burden and highest expected returns for that investment".
For the best-financed universities, seeking the highest expected returns while anticipating losses including some large ones that are tolerable in the sense that they can be absorbed without fundamental disruption of the core mission of the institution seems to be the right answer.
It comes with cake (high expected return), and you get to eat it (lower expected risk).
Higher expected return.
I can figure out that I get a higher expected return and no more risk.
Investing in private securities rather than government bonds provides a higher expected return.
Stocks are riskier, so they have a higher expected return with capital gains and dividends than Treasurys.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com