In the behavioral paradigm, the HMF chicks had a higher elimination rate than the GMF chicks and displayed a significant reduction in overall responsiveness.
SAA-containing HDL has a higher elimination rate than normal HDL, which adds to the efficiency of LPS elimination from circulation.
Furthermore, DDD has a significantly higher elimination rate than DDE and, subsequently, aquatic animals retain more DDE in their bodies [ 60, 61].
It has been shown that in severe hypoalbuminaemic critically ill patients the free fraction of teicoplanin may be more than doubled [ 32], with significantly higher elimination rate [ 33].
In the Japanese studies, a higher elimination rate of meal-related symptoms was also seen with acotiamide, and 100 mg three times a day was established as the optimal dose.
In contrast, the concentrations of lipophilic solutes significantly decrease when the exposure is longer than log t > 0, because of the stronger binding to metabolizing enzymes, resulting in higher elimination rate constants.
In one report, insulin was undetectable in the filtrate despite a high elimination rate and it was suggested that insulin was cleared from the blood by adsorption onto the dialyser membrane (a polysulfone membrane) [ 48].
However, diclofenac was the only contaminant showing an opposite trend to the rest of the compounds, achieving higher elimination rates in the wetlands that exhibited less-oxidizing conditions (VS2p and VGp).
Significantly higher elimination rates were obtained with acotiamide than with placebo for early satiation and for postprandial fullness (table 2).
It was demonstrated that 2 weeks following a unilateral infusion of rotenone into the rat brain, dopamine depletion resulted in lower brain levels and higher elimination rates of DOPAC and HVA for the diseased cerebral hemisphere.
