This is consistent with the efficacy and safety results observed in this study, with a trend toward a somewhat higher effect observed for lipegfilgrastim in terms of anti-neutropenic activity.
Negative, albeit not significant, associations were found for hopanes, with higher effects observed for 7-d (-0.35% (-0.73, 0.03%)) exposures.
The concrete testing results showed that, when the hybrid fiber additive is used, the synergetic effect, that appeared in this case, is higher than effect, observed in fiber individual application.
Due to the high localization effect observed at low temperature, investigation was focused on the PL behavior at T = 10 K as a function of laser incident power Pin. Figure 2 shows the PL spectra of all samples taken at Pin = 10 mW. Figure 2 Spectral PL emission of the investigated samples at P in = 10 mW and T = 10 K.
The high ceiling effect observed on urinary and bowel domains, especially for the function subscale, is congruent with the clinical characteristics of our patient sample.
This could indicate that the initial responder definition, although considered relevant, may have been too easy to reach, resulting in the high placebo effect observed in all the analyses using this definition, and confirms the relevance of performing the post hoc analysis using the tightened responder definition.
This high presumed placebo effect observed in several studies may simply reflect the cyclic nature of CM [22 25].
However, the high (56%) placebo effect observed in this study, greater than in the work by van Rossum et al. [ 4] (42%), also suggests some additional role of psychogenic factors in having an impact on observed changes in HRQL scores.
The highest effect was observed for respiratory diseases and among women aged 75-84 years. 75-84 years
