Sentence examples for highest drug concentration from inspiring English sources

At the highest drug concentration (5 μM), the Doc-loaded oily core NCs (as a reservoir nanosystem) enhanced the native drug cytotoxicity.

The results of in vitro dissolution experiments showed good correlation with mean particle size and crystallinity of the SAS-processed particles, in that the highest drug concentration showed the least dissolution rate and vice versa.

Cells which proliferated at the highest drug concentration within one week were considered chemotherapy refractory.

Three independent experiments were performed in triplicate and a DMSO dilution corresponding to highest drug concentration was assessed in parallel.

Bloodstream trypomastigotes cultured in the presence of DMSO at a dose used to dissolve the highest drug concentration presented no significant effect (Fig. 5).

Finally, the metacyclogenesis assay revealed that the drug present a time and dose-dependent inhibition profile, since in cultures without MDL28170 the number of metacyclic trypomastigotes increased over time, whereas MDL28170 treatment inhibited the differentiation process almost to 50% in the highest drug concentration.

Procaspase-7 was also cleaved, especially for the highest drug concentrations (data not shown).

The drugs were dissolved in DMSO, which was diluted to 0.05% in these media at the highest drug concentrations.

Some samples were essentially unaffected by the highest drug concentrations tested whereas tumor cells from other samples showed decreased viability even at the lowest concentration tested.

The highest drug concentrations without damage to OHCs in culture (ZVAD: 100 mM or Nec-1: 300  μM) were then used in vivo.

The highest drug concentrations to which the cells were exposed were 80, 10, and 20 μg/ml for C, H, and O, respectively.