Sentence examples for highest dosing from inspiring English sources

Control particles (particles without added Cu) showed no toxicity up to the highest dosing.

Subjects in the two highest dosing groups showed improvement in ACR20 (American College of Rheumatology 20% improvement criteria) scores.

The model, however, greatly underpredicted the peak percentage change of P1NP in the highest dosing groups with blosozumab (Supplementary Figure 1, arms 16 and 23).

A larger percentage of patients in each treatment arm had a SBM within 24 hours of initial dosing of lubiprostone compared to placebo; the difference for the two highest dosing groups was statistically significant (placebo group = 27.3%; 24 μg group = 44.8%, 48 μg = 59.4%; (p = 0.009); 72 μg = 63.6%; p = 0.003).

The monograph "Botulinum Toxin Type A for Injection" of the European Pharmacopoeia 7.2 (Council of Europe 2011) states that every production lot of BoNT has to be tested in an LD50 potency test in mice (Fig.  16), where the final dilution series results in the highest dosing killing 90% of animals and the lowest dosing in at least 90% survival.

However, for the one evaluable patient at the highest dosing level (paclitaxel 80 mg m−2, pazopanib 800 mg, and lapatinib 1000 mg), AUC0 24 and Cmax values of lapatinib were lower than the mean values recorded for all other dose levels.

The worst scores were by the people who reported the highest doses of Ecstasy.

The highest dose induced the highest score decrease, (P < 0.01, **).

The highest doses reduced hyperactivity and impulsiveness.

Neutropenia was reported at the highest dose.

High doses can cause fatal renal failure.