Sentence examples for highest dose used from inspiring English sources

In contrast GSK1059865 decreased drinking in air-exposed mice only at the highest dose used.

After an overnight fast, over a period of 1 hour, 4.8 g phenylacetate was ingested, which is the highest dose used to probe Krebs cycle metabolism.

The plasma glucose concentration and production, and the contribution of gluconeogenesis to glucose production, were unaffected by phenylacetate ingestion at the highest dose used to probe Krebs cycle metabolism.

MNK1 inhibitor significantly decreased cell growth rates at the highest dose used (40 µM) in all the cell lines tested (Fig. 9C).

As expected, the induction was stronger with TNF-α than IL-1β and did not reach saturation even at the highest dose used (100 ng/mL), while IL-1β was saturated at 10 ng/mL (Fig. 1b).

However, even at the highest dose used, some pancreatic regions remained negative.

The inhibitory activity of TNF-α was specific to the parasites because TNF-α had no cytotoxic effect on infected or normal HepG2 cells as measured by the MTT assay, even when added at the highest doses used.

Interestingly, REM134 cells incubated with increasing doses of CCL2 showed marginal effects on cell proliferation – 1.2-fold increase in proliferation at the highest doses used – which was not dose-dependent at the stated doses ((Fig. 4a (iii)).

Fauci says he has no hesitation moving forward with the higher dose used in the NIAID study.

The apparently deleterious effect of EPO treatment on LVEF in DCM mice may be due to the high dose used in the present study, which may have induced polycythaemia, resulted in impaired cardiac function.

Each agent has a "high" dose, (used in to treat reticuloendothelial malignancies [13], [14]) and a "low" dose (used to treat "inflammatory" diseases.