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The double mutant exhibited the highest degree of attenuation, with an LD50 160 times that of wild-type B. anthracis.
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Ensuring a very precise centering, such a system should provide a high degree of attenuation of the local seismic noise, which — together with an integration time of the order of tens of days — would allow a test of the WEP with an accuracy improved by at least an order of magnitude with respect to the best measurements achieved so far.
The pks12 (MRA_2063/Rv2048c) is involved in dimycocerosyl phthiocerol synthesis and the disruption of this gene in H37Rv caused high degree of attenuation of virulence in mice [47].
The vaccine strain DV-STM-07 is able to achieve protective immunity without triggering abortion because of its high degree of attenuation and also its ability to not induce inflammation.
We suspected that the vaccine strain has a high degree of attenuation which does not elicit a strong inflammatory response but still is able to evoke a protective immune response.
Allelic exchange of the cpsD gene resulted in reduced capsule, increased chain length, a marked decrease in all capsular monosaccharides, and a high degree of attenuation (31 ).
This suggests that the increasing density of the CNFs does not necessarily increase the specific area (area per unit gram) of the CNFs, and/or it can also decrease the pore size due to the higher degree of entanglement and thus lead to the attenuation of the electrolyte ion diffusion.
However, in a bipollutant model including two local pollutants, there is the potential for bias and attenuation of model coefficients because of a higher degree of variance of exposure error.
There was a high degree of individualism.
A high degree of courtesy is expected.
with a high degree of professional polish.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com