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This finding is explained by the highest connection probability provided by the routes selected by MDORA.
The main outlier is the recurrent L4e to L4e connection, which exhibits the highest connection probability in the study of Lefort et al. (2009), but rather low values in the physiological and particularly the anatomical map.
The fact that these anterior regions of the insula are more involved in language functions is compatible with the fact that this insular territory had the highest connection probability with the key frontal language regions (BA44, BA45, and BA6; see Fig. 6) in our study.
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Probabilistic connectivity mapping revealed a significantly higher connection probability of the right hippocampus with these tracts.
A higher similarity leads to a higher connection probability and, on the other hand, users who get connected become more similar due to the influence that new acquaintances exert on one another.
However, in the semi-supervised scenario, purity itself can be a misleading measure due to high connection probability of the unlabeled vertices.
By knowing in advance the user pairs with higher connection probability, social contact recommendations can be sent to the endpoints, with the aim of notifying the two endpoints of the possibility of establishing a potentially interesting social connection that they may not have noticed otherwise or at least to speed up the linking process between them.
However, this higher connection probability for bidirectional connections for nearby neurons assumes that relevant neurons are available for incoming connections.
Moreover, a high connection probability was found between FS and L2/3 pyramidal neurons (0.33, 3/9 connections tested).
This is a consequence of the Gaussian distribution of axonal termination points, which implies a higher connection probability for close-by cortical neurons.
We hypothesize that the emergence of coarseness clusters in layer 2 3 results from the feed forward connectivity patterns from lower cortical layers, possibly combined with higher connection probabilities between neurons belonging to the same coarseness cluster and dendritic amplification mechanisms (Lavzin et al., 2012).
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